Expandable and Rapidly Differentiating Human Induced Neural Stem Cell Lines for Multiple Tissue Engineering Applications.

Cairns, Dana M.
Chwalek, Karolina.
Moore, Yvonne E.
Kelley, Matthew R.
Abbott, Rosalyn D.
Moss, Stephen.
Kaplan, David, 1953-
2016

Limited availability of human neurons poses a significant barrier to progress in biological and preclinical studies of the human nervous system. Current stem cell-based approaches of neuron generation are still hindered by prolonged culture requirements, protocol complexity, and variability in neuronal differentiation. Here we establish stable human induced neural stem cell (hiNSC) lines through t... read more

Subjects
Stem cells.
Tissue engineering.
Tufts University. Department of Biomedical Engineering.
Permanent URL
http://hdl.handle.net/10427/010557
Original publication
Cairns, D. M., Chwalek, K., Moore, Y. E., Kelley, M. R., Abbott, R. D., Moss, S., & Kaplan, D. L. (2016). Expandable and Rapidly Differentiating Human Induced Neural Stem Cell Lines for Multiple Tissue Engineering Applications. Stem Cell Reports, 7(3), 557-570. doi:10.1016/j.stemcr.2016.07.017.
ID: tufts:19577
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