Two-photon excited fluorescence of intrinsic fluorophores enables label-free assessment of adipose tissue function.

Alonzo, Carlo Amadeo.
Karaliota, Sevasti.
Pouli, Dimitra.
Liu, Zhiyi.
Karalis, Katia P.
Georgakoudi, Irene.
2016

Current methods for evaluating adipose tissue function are destructive or have low spatial resolution. These limit our ability to assess dynamic changes and heterogeneous responses that occur in healthy or diseased subjects, or during treatment. Here, we demonstrate that intrinsic two-photon excited fluorescence enables functional imaging of adipocyte metabolism with subcellular resolution. Steady... read more

Subjects
Fat--Metabolism.
Adipose tissue.
Tufts University. Department of Biomedical Engineering.
Genre
Permanent URL
http://hdl.handle.net/10427/010262
Original publication
Alonzo, C. A. et al. Two-photon excited fluorescence of intrinsic fluorophores enables label-free assessment of adipose tissue function. Sci. Rep. 6, 31012; doi: 10.1038/srep31012 (2016).
ID: tufts:18925
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