Optical metrics of the extracellular matrix predict compositional and mechanical changes after myocardial infarction.

Quinn, Kyle P.
Sullivan, Kelly E.
Liu, Zhiyi.
Ballard, Zachary.
Siokatas, Christos.
Georgakoudi, Irene.
Black, Lauren D., III.
2016

Understanding the organization and mechanical function of the extracellular matrix (ECM) is critical for the development of therapeutic strategies that regulate wound healing following disease or injury. However, these relationships are challenging to elucidate during remodeling following myocardial infarction (MI) due to rapid changes in cellularity and an inability to characterize both ECM micro... read more

Subjects
Extracellular matrix.
Myocardial infarction.
Proteomics.
Tissues.
Tufts University. Department of Biomedical Engineering.
Genre
Permanent URL
http://hdl.handle.net/10427/010259
Original publication
Quinn, K. P. et al. Optical metrics of the extracellular matrix predict compositional and mechanical changes after myocardial infarction. Sci. Rep. 6, 35823; doi: 10.1038/srep35823 (2016).
ID: tufts:18922
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