Performance of the G4 Xpert® MTB/RIF assay for the detection of Mycobacterium tuberculosis and rifampin resistance: a retrospective case-control study of analytical and clinical samples from high- and low-tuberculosis prevalence settings.

Dharan, Nila J.
Blakemore, Robert.
Sloutsky, Alex.
Kaur, Devinder.
Alexander, Richard C.
Ghajar, Minoo.
Musser, Kimberlee A.
Escuyer, Vincent E.
Rowlinson, Marie-Claire.
Crowe, Susanne.
Laniado-Laborin, Rafael.
Valli, Eloise.
Nabeta, Pamela.
Johnson, Pamela.
Alland, David.
2016

Background: The Xpert® MTB/RIF (Xpert) assay is a rapid PCR-based assay for the detection of Mycobacterium tuberculosis complex DNA (MTBc) and mutations associated with rifampin resistance (RIF). An updated version introduced in 2011, the G4 Xpert, included modifications to probe B and updated analytic software.

Permanent URL
http://hdl.handle.net/10427/010152
Original publication
Dharan, Nila, Robert Blakemore, Alex Sloutsky, Devinder Kaur, Richard C. Alexander, Minoo Ghajar, Kimberlee A. Musser, Vincent E. Escuyer, Marie-Claire Rowlinson, Susanne Crowe, Rafael Laniado-Laborin, Eloise Valli, Pamela Nabeta, Pamela Johnson, and David Alland. "Performance of the G4 Xpert® MTB/RIF assay for the detection of Mycobacterium tuberculosis and rifampin resistance: a retrospective case-control study of analytical and clinical samples from high- and low-tuberculosis prevalence settings." BMC Infectious Diseases 16, no. 1 (12, 2016): 1-11.
ID: tufts:18905
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