Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos.

Levin, Michael.
Chernet, Brook T.
Fields, Chris.
2015

In addition to the immediate microenvironment, long-range signaling may be an important component of cancer. Molecular-genetic analyses have implicated gap junctions—key mediators of cell-cell communication—in carcinogenesis. We recently showed that the resting voltage potential of distant cell groups is a key determinant of metastatic transformation and tumor induction. Here, we show in the Xenop... read more

Subjects
Tumors.
Carcinogenesis.
Cancer.
Electrophysiology.
Tufts University. Department of Biology.
Permanent URL
http://hdl.handle.net/10427/009727
Original publication
Chernet BT, Fields C and Levin M (2015) Long-range gap junctional signaling controls oncogene-mediated tumorigenesis in Xenopus laevis embryos. Front. Physiol. 5:519. doi: 10.3389/fphys.2014.00519.
ID: tufts:18174
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