Discovery of substrate cycles in large scale metabolic networks using hierarchical modularity.Hassoun, Soha.
Sridharan, Gautham Vivek.
Background: A substrate cycle is a set of metabolic reactions, arranged in a loop, which does not result in net consumption or production of the metabolites. The cycle operates by transforming a cofactor, e.g. oxidizing a reducing equivalent. Substrate cycles have been found experimentally in many parts of metabolism; however, their physiological roles remain unclear. As genome-scale metabolic mod... read more
- Systems biology.
- Tufts University. Department of Computer Science.
- Permanent URL
- Original publication
- Sridharan, G. V., E. Ullah, S. Hassoun and K. Lee (2015). "Discovery of substrate cycles in large scale metabolic networks using hierarchical modularity." BMC Systems Biology 9(1). doi: 10.1186/s12918-015-0146-2.