A Tunable Silk Hydrogel Device for Studying Limb Regeneration in Adult Xenopus Laevis.

Kaplan, David, 1953-
Golding, Anne.
Guay, Justin A.
Herrera-Rincon, Celia.
Levin, Michael.

In certain amphibian models limb regeneration can be promoted or inhibited by the local wound bed environment. This research introduces a device that can be utilized as an experimental tool to characterize the conditions that promotes limb regeneration in the adult frog (Xenopus laevis) model. In particular, this device was designed to manipulate the local wound environment via a hydrogel insert. ... read more

Xenopus laevis.
Tufts University. Department of Biomedical Engineering.
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Original publication
Golding, A., J. A. Guay, C. Herrera-Rincon, M. Levin and D. L. Kaplan (2016). "A tunable silk hydrogel device for studying limb regeneration in adult Xenopus laevis." PLoS ONE 11(6). doi: 10.1371/journal.pone.0155618.
ID: tufts:17846
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