Acellular Bi-Layer Silk Fibroin Scaffolds Support Tissue Regeneration in a Rabbit Model of Onlay Urethroplasty.

Kaplan, David, 1953-
Chung, Yeun Goo.
Tu, Duong.
Franck, Debra.
Gil, Eun Seok.
Algarrahi, Khalid.
Adam, Rosalyn M.
Estrada Jr., Carlos R.
Mauney, Joshua R.
2014

Acellular scaffolds derived from Bombyx mori silk fibroin were investigated for their ability to support functional tissue regeneration in a rabbit model of urethra repair. A bi-layer silk fibroin matrix was fabricated by a solvent-casting/salt leaching process in combination with silk fibroin film casting to generate porous foams buttressed by homogeneous silk fibroin films. Ventral onlay urethro... read more

Subjects
Tissue engineering.
Biomedical materials.
Urethroplasty.
Urology.
Tufts University. Department of Biomedical Engineering.
Permanent URL
http://hdl.handle.net/10427/009275
Original publication
Chung YG, Tu D, Franck D, Gil ES, Algarrahi K, Adam RM, et al. (2014) Acellular Bi-Layer Silk Fibroin Scaffolds Support Tissue Regeneration in a Rabbit Model of Onlay Urethroplasty. PLoS ONE 9(3): e91592. doi:10.1371/journal.pone.0091592.
ID: tufts:17841
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