Chip-Based Comparison of the Osteogenesis of Human Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem Cells under Mechanical Stimulation.

Kaplan, David, 1953-
Park, Sang-Hyug.
Sim, Woo Young.
Min, Byoung-Hyun.
Yang, Sang Sik.
Khademhosseini, Ali.
2012

Adipose tissue-derived stem cells (ASCs) are considered as an attractive stem cell source for tissue engineering and regenerative medicine. We compared human bone marrow-derived mesenchymal stem cells (hMSCs) and hASCs under dynamic hydraulic compression to evaluate and compare osteogenic abilities. A novel micro cell chip integrated with microvalves and microscale cell culture chambers separated ... read more

Subjects
Stem cells.
Cell differentiation.
Osteogenesis.
Tufts University. Department of Biomedical Engineering.
Permanent URL
http://hdl.handle.net/10427/009273
Original publication
Park S-H, Sim WY, Min B-H, Yang SS, Khademhosseini A, et al. (2012) Chip-Based Comparison of the Osteogenesis of Human Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem Cells under Mechanical Stimulation. PLoS ONE 7(9): e46689. doi:10.1371/journal.pone.0046689.
ID: tufts:17837
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