Robust bioengineered 3D functional human intestinal epithelium.

Kaplan, David, 1953-
Chen, Ying.
Lin, Yinan.
Wang, Qianrui.
Rnjak-Kovacina, Jelena.
Li, Chunmei.
Isberg, Ralph R.
Kumamoto, Carol A.
Mecsas, Joan.
2015

Intestinal functions are central to human physiology, health and disease. Options to study these functions with direct relevance to the human condition remain severely limited when using conventional cell cultures, microfluidic systems, organoids, animal surrogates or human studies. To replicate in vitro the tissue architecture and microenvironments of native intestine, we developed a 3D porous pr... read more

Subjects
Tissue engineering.
Human anatomy--Models.
Intestines.
Tufts University. Department of Biomedical Engineering.
Permanent URL
http://hdl.handle.net/10427/009261
Original publication
Chen, Y. et al. Robust bioengineered 3D functional human intestinal epithelium. Sci. Rep. 5, 13708; doi: 10.1038/srep13708 (2015).
ID: tufts:17825
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