Tumor morphological evolution: directed migration and gain and loss of the self-metastatic phenotype.Enderling, Heiko.
Background: Aside from the stepwise genetic alterations known to underlie cancer cell creation, the microenvironment is known to profoundly influence subsequent tumor development, morphology and metastasis. Invasive cluster formation has been assumed to be dependent on directed migration and a heterogeneous environment - a conclusion deri... read more
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- Original publication
- Enderling, Heiko, Lynn Hlatky, and Philip Hahnfeldt. "Tumor morphological evolution: directed migration and gain and loss of the self-metastatic phenotype." Biology Direct 5, no. 1 (12, 2010): 1-9.