Leptin differentially regulate STAT3 activation in ob/ob mouse adipose mesenchymal stem cells.Zhou, Zhou.
Zhou, Hui Ren.
Claycombe, Kate J.
Background: Leptin-deficient ob/ob mice exhibit adipocyte hypertrophy and hyperplasia as well as elevated adipose tissue and systemic inflammation. Multipotent stem cells isolated from adult adipose tissue can differentiate into adipocytes ex vivo and thereby contribute toward increased adipocyte cell numbers, obesity, and inflamm ation. ... read more
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- Zhou, Zhou, Manish Neupane, Hui Ren Zhou, Dayong Wu, Chia-Cheng Chang, Naima Moustaid-Moussa, and Kate J. Claycombe. "Leptin differentially regulate STAT3 activation in ob/ob mouse adipose mesenchymal stem cells." Nutrition & Metabolism 9, no. 1 (12, 2012): 1-13.