Lack of c-kit receptor promotes mammary tumors in N-nitrosomethylurea-treated Ws/Ws rats.Maffini, Maricel V.
Soto, Ana M.
Theoharides, Theoharis C.
Background: c-kit is expressed in various cell types during development and it has been linked to the promotion of cellular migration, proliferation and/or survival of melanoblasts, hematopoietic progenitors and primordial germ cells. Several reports have proposed a role for the c-kit gene on carcinogenesis. Gain-of-function mutations are... read more
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- Maffini, Maricel, Ana M. Soto, Carlos Sonnenschein, Nikoletta Papadopoulos, and Theoharis C. Theoharides. "Lack of c-kit receptor promotes mammary tumors in N-nitrosomethylurea-treated Ws/Ws rats." Cancer Cell International 8, no. 1 (12, 2008): 1-7.