Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.

Ortega-Azorín, Carolina.
Sorlí, Jose V.
Asensio, Eva M.
Coltell, Oscar.
Martínez-González, Miguel Ángel.
Salas-Salvadó, Jordi.
Covas, Maria-Isabel.
Arós, Fernando.
Lapetra, José.
Serra-Majem, Lluís.
Gómez-Gracia, Enrique.
Fiol, Miquel.
Sáez-Tormo, Guillermo.
Pintó, Xavier.
Muñoz, Miguel Angel.
Ros, Emilio.
Ordovás, Jose M.
Estruch, Ramon.
Corella, Dolores.
2012

Background: Although the Fat Mass and Obesity (FTO) and Melanocortin-4 Receptor (MC4R) genes have been consistently associated with obesity risk, the association between the obesity-risk alleles with type 2 diabetes is still controversial. In some recent meta-analyses in which significant results have been reported, the associations disap... read more

Permanent URL
http://hdl.handle.net/10427/009984
Original publication
Ortega-Azorín, Carolina, Jose V. Sorlí, Eva M. Asensio, Oscar Coltell, Miguel Ángel Martínez-González, Jordi Salas-Salvadó, Maria-Isabel Covas, Fernando Arós, José Lapetra, Lluís Serra-Majem, Enrique Gómez-Gracia, Miquel Fiol, Guillermo Sáez-Tormo, Xavier Pintó, Miguel Angel Muñoz, Emilio Ros, Jose M. Ordovás, Ramon Estruch, and Dolores Corella. "Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low." Cardiovascular Diabetology 11, no. 1 (12, 2012): 1-12.
ID: tufts:17445
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