Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design.

Boghigian, Brett A.
Shi, Hai.
Lee, Kyongbum.
Pfeifer, Blaine A.
2010

Background: Microbial hosts offer a number of unique advantages when used as production systems for both native and heterologous small-molecules. These advantages include high selectivity and benign environmental impact; however, a principal drawback is low yield and/or productivity, which limits economic viability. Therefore a major chal... read more

Permanent URL
http://hdl.handle.net/10427/010231
Original publication
Boghigian, Brett, Hai Shi, Kyongbum Lee, and Blaine A. Pfeifer. "Utilizing elementary mode analysis, pathway thermodynamics, and a genetic algorithm for metabolic flux determination and optimal metabolic network design." BMC Systems Biology 4, no. 1 (12, 2010): 1-17.
ID: tufts:17440
To Cite: DCA Citation Guide
Usage: Detailed Rights