Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects.Smithline, Howard A.
Greenblatt, David J.
Background: High dose oral thiamine may have a role in treating diabetes, heart failure, and hypermetabolic states. The purpose of this study was to determine the pharmacokinetic profile of oral thiamine hydrochloride at 100 mg, 500 mg and 1500 mg doses in healthy subjects.
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- Smithline, Howard, Michael Donnino, and David J. Greenblatt. "Pharmacokinetics of high-dose oral thiamine hydrochloride in healthy subjects." BMC Clinical Pharmacology 12, no. 1 (12, 2012): 1-10.