Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats.

Baker, Stuart G.
Soto, Ana M.
Sonnenschein, Carlos.
Cappuccio, Antonio.
Potter, John D.
Kramer, Barnett S.
2009

Background: There is experimental evidence from animal models favoring the notion that the disruption of interactions between stroma and epithelium plays an important role in the initiation of carcinogenesis. These disrupted interactions are hypothesized to be mediated by molecules, termed morphostats, which diffuse through the tissue to ... read more

Permanent URL
http://hdl.handle.net/10427/010160
Original publication
Baker, Stuart, Ana M. Soto, Carlos Sonnenschein, Antonio Cappuccio, John D. Potter, and Barnett S. Kramer. "Plausibility of stromal initiation of epithelial cancers without a mutation in the epithelium: a computer simulation of morphostats." BMC Cancer 9, no. 1 (12, 2009): 1-11.
ID: tufts:17378
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