In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2.

Jeong, Kwang-il.
Chapman-Bonofiglio, Susan.
Singh, Pradeep.
Lee, Jongo.
Tzipori, Saul.
Sheoran, Abhineet S.
2010

Backgound: Shiga toxin 2 (Stx2), one of two Stx liberated by Stx-producing Escherichia coli, is composed of an A subunit monomer and a B subunit pentamer, and is directly linked with hemolytic uremic syndrome in children. The pentameric B subunit binds to its cell surface receptor Gb3 for toxin internalization, and the A subunit follows i... read more

Permanent URL
http://hdl.handle.net/10427/010097
Original publication
Jeong, Kwang-il, Susan Chapman-Bonofiglio, Pradeep Singh, Jongo Lee, Saul Tzipori, and Abhineet S. Sheoran. "In vitro and in vivo protective efficacies of antibodies that neutralize the RNA N-glycosidase activity of Shiga toxin 2." BMC Immunology 11, no. 1 (12, 2010): 1-9.
ID: tufts:17347
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