Histone deacetylase activity is necessary for left-right patterning during vertebrate development.Carneiro, Katia.
Karger, Barry L.
Barisone, Gustavo A.
Lemire, Joan M.
Background: Consistent asymmetry of the left-right (LR) axis is a crucial aspect of vertebrate embryogenesis. Asymmetric gene expression of the TGFβ superfamily member Nodal related 1 (Nr1) in the left lateral mesoderm plate is a highly conserved step regulating the situs of the heart and viscera. In Xenopus, movement of maternal serotoni... read more
- Permanent URL
- Original publication
- Carneiro, Katia, Claudia Donnet, Tomas Rejtar, Barry L. Karger, Gustavo A. Barisone, Elva Díaz, Sandhya Kortagere, Joan M. Lemire, and Michael Levin. "Histone deacetylase activity is necessary for left-right patterning during vertebrate development." BMC Developmental Biology 11, no. 1 (12, 2011): 1-19.